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Cotranslational folding cooperativity of contiguous domains of α-spectrin

Proteins synthesized in the cell can begin to fold during translation before the entire polypeptide has been produced, which may be particularly relevant to the folding of multidomain proteins. Here, we study the cotranslational folding of adjacent domains from the cytoskeletal protein α-spectrin us...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Kemp, Grant, Nilsson, Ola B., Tian, Pengfei, Best, Robert B., von Heijne, Gunnar
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7322005/
https://ncbi.nlm.nih.gov/pubmed/32513720
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1909683117
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