Activated protein C ameliorates diabetic nephropathy by epigenetically inhibiting the redox enzyme p66(Shc)

The coagulation protease activated protein C (aPC) confers cytoprotective effects in various in vitro and in vivo disease models, including diabetic nephropathy. The nephroprotective effect may be related to antioxidant effects of aPC. However, the mechanism through which aPC may convey these antiox...

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Detaylı Bibliyografya
Asıl Yazarlar: Bock, Fabian, Shahzad, Khurrum, Wang, Hongjie, Stoyanov, Stoyan, Wolter, Juliane, Dong, Wei, Pelicci, Pier Giuseppe, Kashif, Muhammed, Ranjan, Satish, Schmidt, Simone, Ritzel, Robert, Schwenger, Vedat, Reymann, Klaus G., Esmon, Charles T., Madhusudhan, Thati, Nawroth, Peter P., Isermann, Berend
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: National Academy of Sciences 2013
Konular:
Biological Sciences
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3545757/
https://ncbi.nlm.nih.gov/pubmed/23267072
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1218667110
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