Cytoprotective signaling by activated protein C requires protease-activated receptor-3 in podocytes

The cytoprotective effects of activated protein C (aPC) are well established. In contrast, the receptors and signaling mechanism through which aPC conveys cytoprotection in various cell types remain incompletely defined. Thus, within the renal glomeruli, aPC preserves endothelial cells via a proteas...

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書誌詳細
主要な著者: Madhusudhan, Thati, Wang, Hongjie, Straub, Beate K., Gröne, Elisabeth, Zhou, Qianxing, Shahzad, Khurrum, Müller-Krebs, Sandra, Schwenger, Vedat, Gerlitz, Bruce, Grinnell, Brian W., Griffin, John H., Reiser, Jochen, Gröne, Hermann-Josef, Esmon, Charles T., Nawroth, Peter P., Isermann, Berend
フォーマット: Artigo
言語:Inglês
出版事項: American Society of Hematology 2012
主題:
Thrombosis and Hemostasis
オンライン･アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3398751/
https://ncbi.nlm.nih.gov/pubmed/22117049
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2011-07-365973
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