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Activated protein C reverses epigenetically sustained p66(Shc) expression in plaque-associated macrophages in diabetes
Impaired activated protein C (aPC) generation is associated with atherosclerosis and diabetes mellitus. Diabetes-associated atherosclerosis is characterized by the hyperglycaemic memory, e.g., failure of disease improvement despite attenuation of hyperglycaemia. Therapies reversing the hyperglycaemi...
Gardado en:
| Publicado en: | Commun Biol |
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| Main Authors: | , , , , , , , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
Nature Publishing Group UK
2018
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6123684/ https://ncbi.nlm.nih.gov/pubmed/30271984 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s42003-018-0108-5 |
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