Farnesoid X Receptor Agonism Protects against Diabetic Tubulopathy: Potential Add-On Therapy for Diabetic Nephropathy

Established therapies for diabetic nephropathy (dNP) delay but do not prevent its progression. The shortage of established therapies may reflect the inability to target the tubular compartment. The chemical chaperone tauroursodeoxycholic acid (TUDCA) ameliorates maladaptive endoplasmic reticulum (ER...

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Detalhes bibliográficos
Publicado no:J Am Soc Nephrol
Main Authors: Marquardt, Andi, Al-Dabet, Moh’d Mohanad, Ghosh, Sanchita, Kohli, Shrey, Manoharan, Jayakumar, ElWakiel, Ahmed, Gadi, Ihsan, Bock, Fabian, Nazir, Sumra, Wang, Hongjie, Lindquist, Jonathan A., Nawroth, Peter Paul, Madhusudhan, Thati, Mertens, Peter R., Shahzad, Khurrum, Isermann, Berend
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Nephrology 2017
Assuntos:
Brief Communications
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5661274/
https://ncbi.nlm.nih.gov/pubmed/28696246
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2016101123
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