Farnesoid X Receptor Agonism Protects against Diabetic Tubulopathy: Potential Add-On Therapy for Diabetic Nephropathy

Established therapies for diabetic nephropathy (dNP) delay but do not prevent its progression. The shortage of established therapies may reflect the inability to target the tubular compartment. The chemical chaperone tauroursodeoxycholic acid (TUDCA) ameliorates maladaptive endoplasmic reticulum (ER...

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Sparad:
Bibliografiska uppgifter
I publikationen:J Am Soc Nephrol
Huvudupphovsmän: Marquardt, Andi, Al-Dabet, Moh’d Mohanad, Ghosh, Sanchita, Kohli, Shrey, Manoharan, Jayakumar, ElWakiel, Ahmed, Gadi, Ihsan, Bock, Fabian, Nazir, Sumra, Wang, Hongjie, Lindquist, Jonathan A., Nawroth, Peter Paul, Madhusudhan, Thati, Mertens, Peter R., Shahzad, Khurrum, Isermann, Berend
Materialtyp: Artigo
Språk:Inglês
Publicerad: American Society of Nephrology 2017
Ämnen:
Brief Communications
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC5661274/
https://ncbi.nlm.nih.gov/pubmed/28696246
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2016101123
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