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Pkb/Akt1 Mediates Wnt/GSK3β/β-Catenin Signaling-Induced Apoptosis in Human Cord Blood Stem Cells Exposed to Organophosphate Pesticide Monocrotophos

Inhibition mechanisms of protein kinase B (Pkb)/Akt and its consequences on related cell signaling were investigated in human umbilical cord blood stem cells (hUCBSCs) exposed to monocrotophos (MCP, an organophosphate pesticide). In silico data reveal that MCP interacts with kinase and c-terminal re...

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Bibliografske podrobnosti
Main Authors: Kashyap, Mahendra P., Singh, Abhishek K., Kumar, Vivek, Yadav, Dharmendra K., Khan, Feroz, Jahan, Sadaf, Khanna, Vinay K., Yadav, Sanjay, Pant, Aditya B.
Format: Artigo
Jezik:Inglês
Izdano: Mary Ann Liebert, Inc. 2013
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3545351/
https://ncbi.nlm.nih.gov/pubmed/22897592
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/scd.2012.0220
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