Pkb/Akt1 Mediates Wnt/GSK3β/β-Catenin Signaling-Induced Apoptosis in Human Cord Blood Stem Cells Exposed to Organophosphate Pesticide Monocrotophos

Inhibition mechanisms of protein kinase B (Pkb)/Akt and its consequences on related cell signaling were investigated in human umbilical cord blood stem cells (hUCBSCs) exposed to monocrotophos (MCP, an organophosphate pesticide). In silico data reveal that MCP interacts with kinase and c-terminal re...

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Main Authors: Kashyap, Mahendra P., Singh, Abhishek K., Kumar, Vivek, Yadav, Dharmendra K., Khan, Feroz, Jahan, Sadaf, Khanna, Vinay K., Yadav, Sanjay, Pant, Aditya B.
Format: Artigo
Language:Inglês
Published: Mary Ann Liebert, Inc. 2013
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Original Research Reports
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3545351/
https://ncbi.nlm.nih.gov/pubmed/22897592
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/scd.2012.0220
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