Pkb/Akt1 Mediates Wnt/GSK3β/β-Catenin Signaling-Induced Apoptosis in Human Cord Blood Stem Cells Exposed to Organophosphate Pesticide Monocrotophos

Inhibition mechanisms of protein kinase B (Pkb)/Akt and its consequences on related cell signaling were investigated in human umbilical cord blood stem cells (hUCBSCs) exposed to monocrotophos (MCP, an organophosphate pesticide). In silico data reveal that MCP interacts with kinase and c-terminal re...

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Autores principales: Kashyap, Mahendra P., Singh, Abhishek K., Kumar, Vivek, Yadav, Dharmendra K., Khan, Feroz, Jahan, Sadaf, Khanna, Vinay K., Yadav, Sanjay, Pant, Aditya B.
Formato: Artigo
Lenguaje:Inglês
Publicado: Mary Ann Liebert, Inc. 2013
Materias:
Original Research Reports
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3545351/
https://ncbi.nlm.nih.gov/pubmed/22897592
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/scd.2012.0220
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