Pkb/Akt1 Mediates Wnt/GSK3β/β-Catenin Signaling-Induced Apoptosis in Human Cord Blood Stem Cells Exposed to Organophosphate Pesticide Monocrotophos

Inhibition mechanisms of protein kinase B (Pkb)/Akt and its consequences on related cell signaling were investigated in human umbilical cord blood stem cells (hUCBSCs) exposed to monocrotophos (MCP, an organophosphate pesticide). In silico data reveal that MCP interacts with kinase and c-terminal re...

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Hlavní autoři: Kashyap, Mahendra P., Singh, Abhishek K., Kumar, Vivek, Yadav, Dharmendra K., Khan, Feroz, Jahan, Sadaf, Khanna, Vinay K., Yadav, Sanjay, Pant, Aditya B.
Médium: Artigo
Jazyk:Inglês
Vydáno: Mary Ann Liebert, Inc. 2013
Témata:
Original Research Reports
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3545351/
https://ncbi.nlm.nih.gov/pubmed/22897592
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/scd.2012.0220
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