Monocrotophos Induced Apoptosis in PC12 Cells: Role of Xenobiotic Metabolizing Cytochrome P450s

Monocrotophos (MCP) is a widely used organophosphate (OP) pesticide. We studied apoptotic changes and their correlation with expression of selected cytochrome P450s (CYPs) in PC12 cells exposed to MCP. A significant induction in reactive oxygen species (ROS) and decrease in glutathione (GSH) levels...

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Main Authors: Kashyap, Mahendra Pratap, Singh, Abhishek Kumar, Kumar, Vivek, Tripathi, Vinay Kumar, Srivastava, Ritesh Kumar, Agrawal, Megha, Khanna, Vinay Kumar, Yadav, Sanjay, Jain, Swatantra Kumar, Pant, Aditya Bhushan
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2011
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3061860/
https://ncbi.nlm.nih.gov/pubmed/21445290
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0017757
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