trans-Resveratrol Protects Ischemic PC12 Cells by Inhibiting the Hypoxia Associated Transcription Factors and Increasing the Levels of Antioxidant Defense Enzymes

[Image: see text] An in vitro model of ischemic cerebral stroke [oxygen-glucose deprivation (OGD) for 6 h followed by 24 h reoxygenation (R)] with PC12 cells increases Ca(2+) influx by upregulating native L-type Ca(2+) channels and reactive oxygen species (ROS) generation. This reactive oxygen speci...

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Detalhes bibliográficos
Main Authors: Agrawal, Megha, Kumar, Vivek, Singh, Abhishek K., Kashyap, Mahendra P., Khanna, Vinay K., Siddiqui, Maqsood A., Pant, Aditya B.
Formato: Artigo
Idioma:Inglês
Publicado em: American Chemical Society 2012
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3582290/
https://ncbi.nlm.nih.gov/pubmed/23421680
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/cn300143m
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