The interaction of genetic variants and DNA methylation of the interleukin-4 receptor gene increase the risk of asthma at age 18 years

BACKGROUND: The occurrence of asthma is weakly explained by known genetic variants. Epigenetic marks, DNA methylation (DNA-M) in particular, are considered to add to the explanation of asthma. However, no etiological model has yet been developed that integrates genetic variants and DNA-M. To explore...

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Main Authors: Soto-Ramírez, Nelís, Arshad, Syed Hasan, Holloway, John W, Zhang, Hongmei, Schauberger, Eric, Ewart, Susan, Patil, Veeresh, Karmaus, Wilfried
Formato: Artigo
Idioma:Inglês
Publicado: BioMed Central 2013
Assuntos:
Research
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3544634/
https://ncbi.nlm.nih.gov/pubmed/23286427
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1868-7083-5-1
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