Interplay of Filaggrin Loss-of-Function Variants, Allergic Sensitization, and Eczema in a Longitudinal Study Covering Infancy to 18 Years of Age

BACKGROUND: Immune specific genes as well as genes regulating the formation of skin barrier are major determinants for eczema manifestation. There is a debate as to whether allergic sensitization and filaggrin gene (FLG) variants lead to eczema or FLG variants and eczema increase the risk of allergi...

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Detalhes bibliográficos
Main Authors: Ziyab, Ali H., Karmaus, Wilfried, Yousefi, Mitra, Ewart, Susan, Schauberger, Eric, Holloway, John W., Zhang, Hongmei, Arshad, Syed Hasan
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3293849/
https://ncbi.nlm.nih.gov/pubmed/22403702
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0032721
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