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Filaggrin Mutations Increase Allergic Airway Disease in Childhood and Adolescence Through Interactions with Eczema and Aeroallergen Sensitization
BACKGROUND: Filaggrin loss-of-function (FLG-LOF) mutations are an established genetic cause of eczema. These mutations have subsequently been reported to increase the risk of aeroallergen sensitization and allergic airway disease. However, it is unclear whether FLG variants require both eczema and a...
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| Pubblicato in: | Clin Exp Allergy |
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| Autori principali: | , , , , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2018
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5790610/ https://ncbi.nlm.nih.gov/pubmed/29266469 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cea.13077 |
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