Filaggrin Mutations Increase Allergic Airway Disease in Childhood and Adolescence Through Interactions with Eczema and Aeroallergen Sensitization

BACKGROUND: Filaggrin loss-of-function (FLG-LOF) mutations are an established genetic cause of eczema. These mutations have subsequently been reported to increase the risk of aeroallergen sensitization and allergic airway disease. However, it is unclear whether FLG variants require both eczema and a...

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Bibliografiska uppgifter
I publikationen:Clin Exp Allergy
Huvudupphovsmän: Chan, Adrian, Terry, William, Zhang, Hongmei, Karmaus, Wilfried, Ewart, Susan, Holloway, John W., Roberts, Graham, Kurukulaaratchy, Ramesh, Arshad, Syed Hasan
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2018
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Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC5790610/
https://ncbi.nlm.nih.gov/pubmed/29266469
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cea.13077
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