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Interplay of filaggrin loss-of-function variants, allergic sensitization, and eczema in a longitudinal study covering infancy to 18 years of age.

Immune specific genes as well as genes regulating the formation of skin barrier are major determinants for eczema manifestation. There is a debate as to whether allergic sensitization and filaggrin gene (FLG) variants lead to eczema or FLG variants and eczema increase the risk of allergic sensitizat...

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書誌詳細
主要な著者: Ali H Ziyab, Wilfried Karmaus, Mitra Yousefi, Susan Ewart, Eric Schauberger, John W Holloway, Hongmei Zhang, Syed Hasan Arshad
フォーマット: Artigo
言語:Inglês
出版事項: Public Library of Science (PLoS) 2012-01-01
シリーズ:PLoS ONE
オンライン・アクセス:http://europepmc.org/articles/PMC3293849?pdf=render
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