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Interplay of filaggrin loss-of-function variants, allergic sensitization, and eczema in a longitudinal study covering infancy to 18 years of age.
Immune specific genes as well as genes regulating the formation of skin barrier are major determinants for eczema manifestation. There is a debate as to whether allergic sensitization and filaggrin gene (FLG) variants lead to eczema or FLG variants and eczema increase the risk of allergic sensitizat...
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主要な著者: | , , , , , , , |
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フォーマット: | Artigo |
言語: | Inglês |
出版事項: |
Public Library of Science (PLoS)
2012-01-01
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シリーズ: | PLoS ONE |
オンライン・アクセス: | http://europepmc.org/articles/PMC3293849?pdf=render |
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