Oral contraceptives modify the effect of GATA3 polymorphisms on the risk of asthma at the age of 18 years via DNA methylation

BACKGROUND: The prevalence of asthma in girls increases after puberty. Previous studies have detected associations between sex hormones and asthma, as well as between sex hormones and T helper 2 (Th2) asthma-typical immune responses. Therefore, we hypothesized that exogenous or endogenous sex hormon...

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Hlavní autoři: Guthikonda, Kranthi, Zhang, Hongmei, Nolan, Vikki G, Soto-Ramírez, Nelís, Ziyab, Ali H, Ewart, Susan, Arshad, Hasan S, Patil, Veeresh, Holloway, John W, Lockett, Gabrielle A, Karmaus, Wilfried
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2014
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Research
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4171400/
https://ncbi.nlm.nih.gov/pubmed/25250096
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1868-7083-6-17
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