Interaction of prenatal maternal smoking, interleukin 13 genetic variants and DNA methylation influencing airflow and airway reactivity

BACKGROUND: Asthma is characterized by airflow limitation and airway reactivity (AR). Interleukin-13 (IL-13) is involved in the pathogenesis of asthma. Two functional SNPs, rs20541 and rs1800925, of the IL-13 gene (IL13) have been frequently associated with asthma-related lung functions. However, ge...

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Bibliographic Details
Main Authors: Patil, Veeresh K, Holloway, John W, Zhang, Hongmei, Soto-Ramirez, Nelis, Ewart, Susan, Arshad, S Hasan, Karmaus, Wilfried
Format: Artigo
Language:Inglês
Published: BioMed Central 2013
Subjects:
Short Report
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3892084/
https://ncbi.nlm.nih.gov/pubmed/24314122
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1868-7083-5-22
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