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The MTHFR C677T Variant is Associated with Responsiveness to Disulfiram Treatment for Cocaine Dependency
Objective: Disulfiram is a one of the few pharmacotherapies for cocaine addiction that shows promise. Since disulfiram and cocaine both affect levels of global methylation we hypothesized the MTHFR gene, whose product is involved in supplying methyl groups for DNA and protein methylation, may be ass...
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| Главные авторы: | , , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
Frontiers Media S.A.
2013
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3544007/ https://ncbi.nlm.nih.gov/pubmed/23335901 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fpsyt.2012.00109 |
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