The MTHFR C677T Variant is Associated with Responsiveness to Disulfiram Treatment for Cocaine Dependency

Objective: Disulfiram is a one of the few pharmacotherapies for cocaine addiction that shows promise. Since disulfiram and cocaine both affect levels of global methylation we hypothesized the MTHFR gene, whose product is involved in supplying methyl groups for DNA and protein methylation, may be ass...

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Bibliografiska uppgifter
Huvudupphovsmän: Spellicy, Catherine J., Kosten, Thomas R., Hamon, Sara C., Harding, Mark J., Nielsen, David A.
Materialtyp: Artigo
Språk:Inglês
Publicerad: Frontiers Media S.A. 2013
Ämnen:
Psychiatry
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3544007/
https://ncbi.nlm.nih.gov/pubmed/23335901
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fpsyt.2012.00109
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