The MTHFR C677T Variant is Associated with Responsiveness to Disulfiram Treatment for Cocaine Dependency

Objective: Disulfiram is a one of the few pharmacotherapies for cocaine addiction that shows promise. Since disulfiram and cocaine both affect levels of global methylation we hypothesized the MTHFR gene, whose product is involved in supplying methyl groups for DNA and protein methylation, may be ass...

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Detaylı Bibliyografya
Asıl Yazarlar: Spellicy, Catherine J., Kosten, Thomas R., Hamon, Sara C., Harding, Mark J., Nielsen, David A.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Frontiers Media S.A. 2013
Konular:
Psychiatry
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3544007/
https://ncbi.nlm.nih.gov/pubmed/23335901
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fpsyt.2012.00109
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