Pharmacogenetic role of dopamine transporter (SLC6A3) variation on response to disulfiram treatment for cocaine addiction

BACKGROUND AND OBJECTIVES: Disulfiram has been beneficial in treating cocaine addiction in several studies. Patients with two SLC6A3 (DAT1) rs28363170 10-repeat alleles who have with genetically high dopamine transporter (DAT) levels may benefit from increased dopamine levels resulting from disulfir...

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Detalhes bibliográficos
Publicado no:Am J Addict
Main Authors: Kampangkaew, June P., Spellicy, Catherine J., Nielsen, Ellen M., Harding, Mark J., Ye, An, Hamon, Sara C., Kosten, Thomas R., Nielsen, David A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6591035/
https://ncbi.nlm.nih.gov/pubmed/31087723
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/ajad.12891
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