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Pharmacogenetic Randomized Trial for Cocaine Abuse: Disulfiram and dopamine β-hydroxylase
BACKGROUND: Disulfiram has been an effective cocaine addiction pharmacotherapy, and one of its possible mechanisms of efficacy is through copper chelation and inhibition of an enzyme involved in catecholamine metabolism, dopamine β-hydroxylase (DβH), which converts dopamine to norepinephrine. A vari...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3514624/ https://ncbi.nlm.nih.gov/pubmed/22906516 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biopsych.2012.07.011 |
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