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The MTHFR C677T Variant is Associated with Responsiveness to Disulfiram Treatment for Cocaine Dependency

Objective: Disulfiram is a one of the few pharmacotherapies for cocaine addiction that shows promise. Since disulfiram and cocaine both affect levels of global methylation we hypothesized the MTHFR gene, whose product is involved in supplying methyl groups for DNA and protein methylation, may be ass...

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Detalhes bibliográficos
Main Authors: Spellicy, Catherine J., Kosten, Thomas R., Hamon, Sara C., Harding, Mark J., Nielsen, David A.
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3544007/
https://ncbi.nlm.nih.gov/pubmed/23335901
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fpsyt.2012.00109
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