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Modifying Role of Serotonergic 5-HTTLPR & TPH2 Variants on Disulfiram Treatment of Cocaine Addiction: A Preliminary Study

Disulfiram is a cocaine pharmacotherapy that may act through increasing serotonin, benefiting patients with genetically low serotonin transporter levels (5-HTTLPR S′ allele carriers) and low serotonin synthesis (TPH2 A allele carriers). We stabilized 71 cocaine and opioid co-dependent patients on me...

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Bibliographic Details
Main Authors: Nielsen, D.A., Harding, M. J., Hamon, S.C., Huang, W., Kosten, T.R.
Format: Artigo
Language:Inglês
Published: 2012
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3521860/
https://ncbi.nlm.nih.gov/pubmed/22925276
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1601-183X.2012.00839.x
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