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Pharmacogenetic Randomized Trial for Cocaine Abuse: Disulfiram and α(1A)-adrenoceptor gene variation
Disulfiram is a cocaine addiction pharmacotherapy that inhibits dopamine β-hydroxylase (DβH) and reduces norepinephrine production. We examined whether a functional variant of the ADRA1A gene (Cys to Arg at codon 347 in exon 2, Cys347Arg) may enhance treatment response through decreased stimulation...
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| Hauptverfasser: | , , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2013
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3818518/ https://ncbi.nlm.nih.gov/pubmed/23849431 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.euroneuro.2013.05.014 |
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