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κ-opioid Receptor Gene as a Predictor of Response in a Cocaine Vaccine Clinical Trial

OBJECTIVES: We examined a pharmacogenetic association between a variant in the κ-opioid receptor (OPRK1) gene and the response to treatment with a cocaine vaccine tested in a recent clinical trial. This gene has a protective allele for opiate addiction that may act by inhibiting dopamine activation...

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Detalhes bibliográficos
Main Authors: Nielsen, D.A., Hamon, S.C., Kosten, T.R.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3885873/
https://ncbi.nlm.nih.gov/pubmed/23995774
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/YPG.0000000000000008
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