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Pharmacogenetics of Dopamine β-Hydroxylase in Cocaine Dependence Therapy with Doxazosin
BACKGROUND: The α(1) adrenergic antagonist, doxazosin, has improved cocaine use disorder (CUD) presumably by blocking norepinephrine (NE) stimulation and reward from cocaine-induced NE increases. If the NE levels for release were lower, then doxazosin might more readily block this NE stimulation and...
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| Veröffentlicht in: | Addict Biol |
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| Hauptverfasser: | , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2018
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6119656/ https://ncbi.nlm.nih.gov/pubmed/29498170 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/adb.12611 |
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