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The human proton-coupled folate transporter: Biology and therapeutic applications to cancer

This review summarizes the biology of the proton-coupled folate transporter (PCFT). PCFT was identified in 2006 as the primary transporter for intestinal absorption of dietary folates, as mutations in PCFT are causal in hereditary folate malabsorption (HFM) syndrome. Since 2006, there have been majo...

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Detalhes bibliográficos
Main Authors: Desmoulin, Sita Kugel, Hou, Zhanjun, Gangjee, Aleem, Matherly, Larry H.
Formato: Artigo
Idioma:Inglês
Publicado em: Landes Bioscience 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3542225/
https://ncbi.nlm.nih.gov/pubmed/22954694
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/cbt.22020
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