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Conditional Inactivation of Pten with EGFR Overexpression in Schwann Cells Models Sporadic MPNST

The genetic mechanisms involved in the transformation from a benign neurofibroma to a malignant sarcoma in patients with neurofibromatosis-type-1- (NF1-)associated or sporadic malignant peripheral nerve sheath tumors (MPNSTs) remain unclear. It is hypothesized that many genetic changes are involved...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Keng, Vincent W., Watson, Adrienne L., Rahrmann, Eric P., Li, Hua, Tschida, Barbara R., Moriarity, Branden S., Choi, Kwangmin, Rizvi, Tilat A., Collins, Margaret H., Wallace, Margaret R., Ratner, Nancy, Largaespada, David A.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Hindawi Publishing Corporation 2012
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3539440/
https://ncbi.nlm.nih.gov/pubmed/23319880
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2012/620834
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