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CK2 blockade causes MPNST cell apoptosis and promotes degradation of β-catenin
Malignant peripheral nerve sheath tumors (MPNSTs) are soft tissue sarcomas that are a major cause of mortality of Neurofibromatosis type 1 (NF1) patients. MPNST patients have few therapeutic options available and only complete surgical resection can be curative. MPNST formation and survival are depe...
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| Publié dans: | Oncotarget |
|---|---|
| Auteurs principaux: | , , , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Impact Journals LLC
2016
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5288178/ https://ncbi.nlm.nih.gov/pubmed/27448963 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.10668 |
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