An ShRNA Screen Identifies MEIS1 as a Driver of Malignant Peripheral Nerve Sheath Tumors()

Malignant peripheral nerve sheath tumors (MPNST) are rare soft tissue sarcomas that are a major source of mortality in neurofibromatosis type 1 (NF1) patients. To identify MPNST driver genes, we performed a lentiviral short hairpin (sh) RNA screen, targeting all 130 genes up-regulated in neurofibrom...

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Detalhes bibliográficos
Publicado no:EBioMedicine
Main Authors: Patel, Ami V., Chaney, Katherine E., Choi, Kwangmin, Largaespada, David A., Kumar, Ashish R., Ratner, Nancy
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2016
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4972548/
https://ncbi.nlm.nih.gov/pubmed/27333032
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ebiom.2016.06.007
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