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Fatty acid synthase is a metabolic oncogene targetable in malignant peripheral nerve sheath tumors
BACKGROUND: Malignant peripheral nerve sheath tumors (MPNSTs) are soft tissue sarcomas with minimal therapeutic opportunities. We observed that lipid droplets (LDs) accumulate in human MPNST cell lines and in primary human tumor samples. The goal of this study was to investigate the relevance of lip...
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| Publicado no: | Neuro Oncol |
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| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4633928/ https://ncbi.nlm.nih.gov/pubmed/26116612 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nov076 |
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