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Malignant Peripheral Nerve Sheath Tumors
Malignant peripheral nerve sheath tumors (MPNST) are uncommon, biologically aggressive soft tissue sarcomas of neural origin that pose tremendous challenges to effective therapy. In 50% of cases, they occur in the context of neurofibromatosis type I, characterized by loss of function mutations to th...
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| Hauptverfasser: | , , , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
AlphaMed Press
2014
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3926794/ https://ncbi.nlm.nih.gov/pubmed/24470531 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1634/theoncologist.2013-0328 |
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