Malignant Peripheral Nerve Sheath Tumors

Malignant peripheral nerve sheath tumors (MPNST) are uncommon, biologically aggressive soft tissue sarcomas of neural origin that pose tremendous challenges to effective therapy. In 50% of cases, they occur in the context of neurofibromatosis type I, characterized by loss of function mutations to th...

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Bibliographic Details
Main Authors: Farid, Mohamad, Demicco, Elizabeth G., Garcia, Roberto, Ahn, Linda, Merola, Pamela R., Cioffi, Angela, Maki, Robert G.
Format: Artigo
Language:Inglês
Published: AlphaMed Press 2014
Subjects:
Sarcomas
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3926794/
https://ncbi.nlm.nih.gov/pubmed/24470531
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1634/theoncologist.2013-0328
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