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WNT5A inhibition alters the malignant peripheral nerve sheath tumor microenvironment and enhances tumor growth
Malignant peripheral nerve sheath tumors (MPNST) are aggressive soft-tissue sarcomas that cause significant mortality in adults with Neurofibromatosis Type 1 (NF1). We compared gene expression of growth factors in normal human nerves to MPNST and normal human Schwann cells (NHSC) to MPNST cell lines...
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| Publicado no: | Oncogene |
|---|---|
| Main Authors: | , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2021
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8217297/ https://ncbi.nlm.nih.gov/pubmed/34079083 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41388-021-01773-x |
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