CK2 blockade causes MPNST cell apoptosis and promotes degradation of β-catenin

Malignant peripheral nerve sheath tumors (MPNSTs) are soft tissue sarcomas that are a major cause of mortality of Neurofibromatosis type 1 (NF1) patients. MPNST patients have few therapeutic options available and only complete surgical resection can be curative. MPNST formation and survival are depe...

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Sparad:
Bibliografiska uppgifter
I publikationen:Oncotarget
Huvudupphovsmän: Kendall, Jed J., Chaney, Katherine E., Patel, Ami V., Rizvi, Tilat A., Largaespada, David A., Ratner, Nancy
Materialtyp: Artigo
Språk:Inglês
Publicerad: Impact Journals LLC 2016
Ämnen:
Research Paper
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC5288178/
https://ncbi.nlm.nih.gov/pubmed/27448963
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.10668
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