Reprogramming DNA methylation in the mammalian life cycle: building and breaking epigenetic barriers

In mammalian development, epigenetic modifications, including DNA methylation patterns, play a crucial role in defining cell fate but also represent epigenetic barriers that restrict developmental potential. At two points in the life cycle, DNA methylation marks are reprogrammed on a global scale, c...

Full description

Saved in:
Bibliographic Details
Main Authors: Seisenberger, Stefanie, Peat, Julian R., Hore, Timothy A., Santos, Fátima, Dean, Wendy, Reik, Wolf
Format: Artigo
Language:Inglês
Published: The Royal Society 2013
Subjects:
Part II: Molecular mechanisms working in the mammalian life cycle
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3539359/
https://ncbi.nlm.nih.gov/pubmed/23166394
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1098/rstb.2011.0330
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items