Conservation of methylation reprogramming in mammalian development: Aberrant reprogramming in cloned embryos

Mouse embryos undergo genome-wide methylation reprogramming by demethylation in early preimplantation development, followed by remethylation thereafter. Here we show that genome-wide reprogramming is conserved in several mammalian species and ask whether it also occurs in embryos cloned with the use...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Dean, Wendy, Santos, Fátima, Stojkovic, Miodrag, Zakhartchenko, Valeri, Walter, Jörn, Wolf, Eckhard, Reik, Wolf
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: The National Academy of Sciences 2001
Pynciau:
Biological Sciences
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC61110/
https://ncbi.nlm.nih.gov/pubmed/11717434
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.241522698
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