The Dynamics of Genome-wide DNA Methylation Reprogramming in Mouse Primordial Germ Cells

Genome-wide DNA methylation reprogramming occurs in mouse primordial germ cells (PGCs) and preimplantation embryos, but the precise dynamics and biological outcomes are largely unknown. We have carried out whole-genome bisulfite sequencing (BS-Seq) and RNA-Seq across key stages from E6.5 epiblast to...

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Detalhes bibliográficos
Main Authors: Seisenberger, Stefanie, Andrews, Simon, Krueger, Felix, Arand, Julia, Walter, Jörn, Santos, Fátima, Popp, Christian, Thienpont, Bernard, Dean, Wendy, Reik, Wolf
Formato: Artigo
Idioma:Inglês
Publicado em: Cell Press 2012
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3533687/
https://ncbi.nlm.nih.gov/pubmed/23219530
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2012.11.001
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