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Reprogramming DNA methylation in the mammalian life cycle: building and breaking epigenetic barriers
In mammalian development, epigenetic modifications, including DNA methylation patterns, play a crucial role in defining cell fate but also represent epigenetic barriers that restrict developmental potential. At two points in the life cycle, DNA methylation marks are reprogrammed on a global scale, c...
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| Autores principales: | , , , , , |
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| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
The Royal Society
2013
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3539359/ https://ncbi.nlm.nih.gov/pubmed/23166394 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1098/rstb.2011.0330 |
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