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Epigenetic reprogramming in plant and animal development

Epigenetic modifications of the genome are generally stable in somatic cells of multicellular organisms. In germ cells and early embryos, however, epigenetic reprogramming occurs on a genome-wide scale, which includes demethylation of DNA and remodeling of histones and their modifications. Mechanism...

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Bibliographic Details
Main Authors: Feng, Suhua, Jacobsen, Steven E., Reik, Wolf
Format: Artigo
Language:Inglês
Published: 2010
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2989926/
https://ncbi.nlm.nih.gov/pubmed/21030646
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.1190614
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