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Epigenetic reprogramming in plant and animal development

Epigenetic modifications of the genome are generally stable in somatic cells of multicellular organisms. In germ cells and early embryos, however, epigenetic reprogramming occurs on a genome-wide scale, which includes demethylation of DNA and remodeling of histones and their modifications. Mechanism...

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Détails bibliographiques
Auteurs principaux: Feng, Suhua, Jacobsen, Steven E., Reik, Wolf
Format: Artigo
Langue:Inglês
Publié: 2010
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2989926/
https://ncbi.nlm.nih.gov/pubmed/21030646
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.1190614
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