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Defining molecular cornerstones during fibroblast to iPS cell reprogramming in mouse

Ectopic expression of the transcription factors Oct4, Sox2, c-myc and Klf4 in fibroblasts generates induced pluripotent stem (iPS) cells. Little is known about the nature and sequence of molecular events accompanying nuclear reprogramming. Using novel doxycycline-inducible vectors, we have shown tha...

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Bibliografske podrobnosti
Main Authors: Stadtfeld, Matthias, Maherali, Nimet, Hochedlinger, Konrad
Format: Artigo
Jezik:Inglês
Izdano: 2008
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3538379/
https://ncbi.nlm.nih.gov/pubmed/18371448
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stem.2008.02.001
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