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Immortalization eliminates a roadblock during cellular reprogramming into iPS cells
The overexpression of defined transcription factors in somatic cells results in their reprogramming into induced pluripotent stem (iPS) cells(1–3). The extremely low efficiency and slow kinetics of in vitro reprogramming suggest that additional rare events are required to generate iPS cells. The nat...
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| Main Authors: | , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3987892/ https://ncbi.nlm.nih.gov/pubmed/19668190 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature08285 |
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