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A reprogrammable mouse strain from gene targeted embryonic stem cells
The derivation of induced pluripotent stem cells (iPSCs) usually involves the viral introduction of reprogramming factors into somatic cells. Here, we used gene targeting to generate a mouse strain with a single copy of an inducible, polycistronic reprogramming cassette, allowing for the induction o...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2009
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3987893/ https://ncbi.nlm.nih.gov/pubmed/20010832 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nmeth.1409 |
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