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Gene Targeting in Mouse Embryonic Stem Cells
The scientific value of a mouse model with a targeted mutation depends greatly upon how carefully the mutation has been engineered. Until recently, our ability to alter the mouse genome has been limited by both the lack of technologies to conditionally target a locus and by conventional cloning. The...
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| Publicado no: | Methods Mol Biol |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7282145/ https://ncbi.nlm.nih.gov/pubmed/19266325 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/978-1-59745-471-1_8 |
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