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Gene Targeting in Mouse Embryonic Stem Cells

The scientific value of a mouse model with a targeted mutation depends greatly upon how carefully the mutation has been engineered. Until recently, our ability to alter the mouse genome has been limited by both the lack of technologies to conditionally target a locus and by conventional cloning. The...

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Bibliografski detalji
Izdano u:Methods Mol Biol
Glavni autori: Tessarollo, Lino, Palko, Mary Ellen, Akagi, Keiko, Coppola, Vincenzo
Format: Artigo
Jezik:Inglês
Izdano: 2009
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7282145/
https://ncbi.nlm.nih.gov/pubmed/19266325
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/978-1-59745-471-1_8
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