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Gene Targeting in Mouse Embryonic Stem Cells

The scientific value of a mouse model with a targeted mutation depends greatly upon how carefully the mutation has been engineered. Until recently, our ability to alter the mouse genome has been limited by both the lack of technologies to conditionally target a locus and by conventional cloning. The...

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Vydáno v:Methods Mol Biol
Hlavní autoři: Tessarollo, Lino, Palko, Mary Ellen, Akagi, Keiko, Coppola, Vincenzo
Médium: Artigo
Jazyk:Inglês
Vydáno: 2009
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7282145/
https://ncbi.nlm.nih.gov/pubmed/19266325
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/978-1-59745-471-1_8
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