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Fibroblast-Derived Induced Pluripotent Stem Cells Show No Common Retroviral Vector Insertions
Several laboratories have reported the reprogramming of mouse and human fibroblasts into pluripotent cells, using retroviruses carrying the Oct4, Sox2, Klf4, and c-Myc transcription factor genes. In these experiments the frequency of reprogramming was lower than 0.1% of the infected cells, raising t...
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| Główni autorzy: | , , , , , , , , |
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| Format: | Artigo |
| Język: | Inglês |
| Wydane: |
Wiley Subscription Services, Inc., A Wiley Company
2009
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| Hasła przedmiotowe: | |
| Dostęp online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2729671/ https://ncbi.nlm.nih.gov/pubmed/19008347 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1634/stemcells.2008-0696 |
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