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Defining molecular cornerstones during fibroblast to iPS cell reprogramming in mouse
Ectopic expression of the transcription factors Oct4, Sox2, c-myc and Klf4 in fibroblasts generates induced pluripotent stem (iPS) cells. Little is known about the nature and sequence of molecular events accompanying nuclear reprogramming. Using novel doxycycline-inducible vectors, we have shown tha...
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| Main Authors: | , , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
2008
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3538379/ https://ncbi.nlm.nih.gov/pubmed/18371448 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stem.2008.02.001 |
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