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Multimechanistic Tumor Targeted Oncolytic Virus Overcomes Resistance in Brain Tumors
Only a subset of cancer patients inoculated with oncolytic herpes simplex virus (oHSV) type-1 has shown objective response in phase 1 and 2 clinical trials. This has raised speculations whether resistance of tumor cells to oHSV therapy may be a limiting factor. In this study, we have identified esta...
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| Main Authors: | , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3538303/ https://ncbi.nlm.nih.gov/pubmed/22929661 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mt.2012.175 |
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