TMIC-25. MODIFICATION OF EXTRACELLULAR MATRIX ENHANCES ONCOLYTIC ADENOVIRUS IMMUNOTHERAPY IN GLIOBLASTOMA

Complex interplay between heterogeneous cells and extracellular matrix (ECM) in the tumor microenvironment drives the pathogenesis of glioblastoma (GBM). Glycosaminoglycan hyaluronic acid (HA) is a major component of GBM ECM, and is associated with tumor growth, invasion, and resistance to treatment...

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Vydáno v:Neuro Oncol
Hlavní autoři: Kiyokawa, Juri, Kawamura, Yoichiro, Martuza, Robert, Rabkin, Samuel, Shah, Khalid, Wakimoto, Hiroaki
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2019
Témata:
Tumor Microenvironment
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6846609/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noz175.1059
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