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TMIC-25. MODIFICATION OF EXTRACELLULAR MATRIX ENHANCES ONCOLYTIC ADENOVIRUS IMMUNOTHERAPY IN GLIOBLASTOMA

Complex interplay between heterogeneous cells and extracellular matrix (ECM) in the tumor microenvironment drives the pathogenesis of glioblastoma (GBM). Glycosaminoglycan hyaluronic acid (HA) is a major component of GBM ECM, and is associated with tumor growth, invasion, and resistance to treatment...

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Detalhes bibliográficos
Publicado no:Neuro Oncol
Main Authors: Kiyokawa, Juri, Kawamura, Yoichiro, Martuza, Robert, Rabkin, Samuel, Shah, Khalid, Wakimoto, Hiroaki
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6846609/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noz175.1059
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