TMIC-25. MODIFICATION OF EXTRACELLULAR MATRIX ENHANCES ONCOLYTIC ADENOVIRUS IMMUNOTHERAPY IN GLIOBLASTOMA

Complex interplay between heterogeneous cells and extracellular matrix (ECM) in the tumor microenvironment drives the pathogenesis of glioblastoma (GBM). Glycosaminoglycan hyaluronic acid (HA) is a major component of GBM ECM, and is associated with tumor growth, invasion, and resistance to treatment...

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Bibliografske podrobnosti
izdano v:Neuro Oncol
Main Authors: Kiyokawa, Juri, Kawamura, Yoichiro, Martuza, Robert, Rabkin, Samuel, Shah, Khalid, Wakimoto, Hiroaki
Format: Artigo
Jezik:Inglês
Izdano: Oxford University Press 2019
Teme:
Tumor Microenvironment
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6846609/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noz175.1059
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