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Transient fasting enhances replication of oncolytic herpes simplex virus in glioblastoma

Short-term nutritional restriction (fasting) has been shown to enhance the efficacy of chemotherapy by sensitizing cancer cells and protecting normal cells in a variety of cancer models, including glioblastoma (GBM). Cancer cells, unlike normal cells, respond to fasting by promoting oncogenic signal...

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Bibliographic Details
Published in:Am J Cancer Res
Main Authors: Esaki, Shinichi, Rabkin, Samuel D, Martuza, Robert L, Wakimoto, Hiroaki
Format: Artigo
Language:Inglês
Published: e-Century Publishing Corporation 2016
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4859661/
https://ncbi.nlm.nih.gov/pubmed/27186404
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